Rogue pharmacies are not licensed to sell in the United States and put you at risk of counterfeit or tainted drugs How Many Online Pharmacies Are There? There’s a difference between using the Internet to purchase from a retail pharmacy and purchasing from a pharmacy that only has an Internet presence. If you have a heart condition. First and foremost, be sure that whichever online pharmacy you choose is legitimate, safe, and secure. Online pharmacies can be broadly categorized as: Mail-order pharmacies are operated by pharmacy benefits managers PBMs on behalf of health insurers or providers. Online Pharmacy or Pharmacy Online?Express Scripts, Medco, and Caremark (which is owned by CVS) are mail-order pharmacy companies. Purchasing from them, through your insurer, is as safe as using your local . GO TO PHARMACY. The total price includes shipping fees which typically cover an entire order, making it more economical to purchase multiple medications in the same order. . While you’ve likely used a brick-and-mortar pharmacy to get your prescriptions, online pharmacies can be a convenient and efficient way to get the medications you need. .