You’ll soon start receiving the latest Mayo Clinic health information you requested in your inbox. You can use Cialis on a daily basis at a lower dosage. Tadalafil will make these symptoms less severe and reduce the chance that prostate surgery will be needed. How can I buy tadalafil? Counterfeit medicines can be very dangerous. Avoid eating a large meal or a lot of food, as this can slow down the effects of the drug. Tadalafil works for these conditions by promoting muscle relaxation, which improves blood flow in PAH and urinary flow in BPH.A newer form of the medicine that dissolves on the tongue might work faster than the pill that you swallow. Tadalafil (Cialis). This medication is taken with or without food an hour before sex. It works for up to 36 hours. You can take it in a small dose daily or in a larger dose as needed. Avanafil (Stendra). Generic Cialis, or Tadalafil, is available in several doses in tablet form: milligrams (mg), 5 mg, 10 mg, and 20 mg. Depending on the dose for ED, you can use it as needed before sexual. Tadalafil (Cialis) is used to treat erectile dysfunction (ED, impotence; inability to get or keep an erection), and the symptoms of benign prostatic hyperplasia (BPH; an enlarged prostate) which include difficulty urinating (hesitation, dribbling, weak stream, and incomplete bladder emptying), painful urination, and urinary frequency and urgency in adult men.