Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. To provide you with the most relevant and helpful information, and understand which information is beneficial, we may combine your email and site usage information with other information we have about you. Society and culture[ edit ] Marketing[ edit ] Cialis 5mg UK pack of 28 tablets In the United States, the FDA relaxed rules on prescription drug marketing in , allowing advertisements targeted directly to consumers. You may take this medicine with or without food. Tadalafil treats PAH by relaxing the blood vessels in the lungs to allow blood to flow more easily. Also tell your doctor if you have or have ever had pulmonary veno-occlusive disease PVOD; blockage of veins in the lungs ; any condition that affects the shape of the penis; diabetes; high cholesterol; high or low blood pressure; irregular heartbeat; a heart attack or heart failure; angina chest pain ; a stroke; ulcers in the stomach; a bleeding disorder; blood circulation problems; blood cell problems such as sickle cell anemia a disease of the red blood cells , multiple myeloma cancer of the plasma cells , or leukemia cancer of the white blood cells ; or heart, kidney, or liver disease. Tell your doctor if any of these symptoms are severe or do not go away: headache.Cialis (tadalafil) is a moderately priced drug used to treat erection problems in men. It may also be used to treat the enlargement of the prostate gland. This drug is slightly more popular than comparable drugs. It is available in both brand and generic versions. The maximum dose is 10 mg not more than once in every 48 hours. CrCl less than 30 mL/min or on hemodialysis: The maximum dose is 5 mg orally once every 72 hours. Once a day use for ED: CrCl 30 mL/min or greater: Data not available. CrCl less than 30 mL/min or on hemodialysis: Not recommended. Once a day use for BPH. Tadalafil (Cialis) is used to treat erectile dysfunction (ED, impotence; inability to get or keep an erection), and the symptoms of benign prostatic hyperplasia (BPH; an enlarged prostate) which include difficulty urinating (hesitation, dribbling, weak stream, and incomplete bladder emptying), painful urination, and urinary frequency and urgency in adult men.