More recently, there has been increased attention paid to the psychosocial consequences of PE, its epidemiology, its aetiology and its pathophysiology by clinicians and the pharmaceutical industry [ Giuliano et al. Information given here is based on the salt content of the medicine. Store in a cool, dry place, away from direct heat and light. You will find a full list in the manufacturer’s information leaflet supplied with your medicine. This is available via password on the internet www.Dapoxetine is a selective serotonin reuptake inhibitor specifically designed to treat PE. This paper reviews the current evidence for use of dapoxetine in the treatment of PE in adult men. This review encompasses studies of dapoxetine pharmacokinetics, animal studies, human phase I, II and III studies, independent postmarketing and pharmacovigilance efficacy and safety studies and drug-interaction studies. Dapoxetine is a potent SSRI which is administered on demand 1–3 h prior to planned sexual contact. Dapoxetine is a medicine used for the treatment of premature ejaculation (a sexual dysfunction in which a man ejaculates too quickly during sexual intercourse). This medicine helps in increasing the time taken to ejaculate and achieving better control over ejaculation during sexual intercourse.