Instead, breathe freely during the exercises. Both actions use your pelvic floor muscles. All three integrated analyses found significant improvements in satisfaction with sexual intercourse at study endpoint. SSRI-induced sexual dysfunction: fluoxetine, paroxetine, sertraline, and fluvoxamine in a prospective, multicenter, and descriptive clinical study of patients. For best results, focus on tightening only your pelvic floor muscles.We systematically searched Embase, PubMed, Cochrane, of Knowledge, and Clinical for studies reporting dapoxetine in men with premature ejaculation. Efficacy endpoints included intravaginal ejaculatory latency times (IELT), personal distress related to ejaculation (PDRE) and treatment-emergent adverse events (TEAEs) was. Efficacy and safety of dapoxetine in men with premature ejaculation and concomitant erectile dysfunction treated with a phosphodiesterase type 5 inhibitor: randomized, placebo-controlled, phase. Dapoxetine (Priligy TM, Johnson and Johnson, Raritan, NJ) is the first and only product licensed for the treatment of premature ejaculation (PE) in men aged 18–64 years.