Leukemia blood related cancer or Multiple myeloma blood related cancer or Sickle-cell anemia blood disorder —Sildenafil should be used with caution in these patients as problems with prolonged erection of the penis may occur. Angina severe chest pain , unstable or Arrhythmia irregular heartbeat, within the last 6 months or Blood vessel problems eg, aortic stenosis, idiopathic subaortic stenosis or Heart attack within the last 6 months or Heart failure or Hypertension high blood pressure or Hypotension low blood pressure or Retinal disorders eye problem or Retinitis pigmentosa an inherited eye disorder or Stroke within the last 6 months —Should not be used in patients with these conditions. Consumption of sildenafil with illicit drugs was also reported. The mean age of the participants was 37 years range 22— Children 1 year of age and older weighing 20 kg or less—10 mg 3 times a day. The majority of recreational EDM users reported mixing EDMs with illicit drugs and particularly during risky sexual behaviors 8.For oral dosage forms (suspension or tablets): Adults—20 milligrams (mg) 3 times a day. Your doctor may adjust your dose as needed and tolerated. However, the dose is usually not more than 80 mg 3 times a day. Children 1 year of age and older weighing 45 kilograms (kg) or more—20 mg 3 times a day. Sildenafil is used to treat erectile dysfunction (ED) and to reduce blood pressure in pulmonary arterial hypertension (PAH). It is taken when needed for ED and daily for PAH. A headache, stomach upsets, and flushing are the main side effects, and it should not be taken within 24 hours of a nitrate. 5. Tips. This means that 4 hours after you take a dose, your body has cleared half of the dose. In most cases, it takes about 5 half-lives for your body to completely remove a drug from your system. So.