Viagra Connect helps the blood vessels around the penis relax and expand, increasing blood flow. How oral medicines differ Each oral medicine for ED has a slightly different chemical makeup. It is not uncommon to experience side effects when taking Viagra Connect. They also report feeling more satisfied with their sex lives, which can lead to improved relationships and a better overall sense of well-being. Some of the most common side effects when taking Viagra Connect include: Headaches. He started taking Tadalafil daily and noticed a significant improvement in his sexual function within a few weeks. Discussing potential risks and benefits with your healthcare provider is essential before starting a daily regimen of Tadalafil.How Viagra Connect Works. Viagra Connect helps men to attain and maintain an erection after being sexually stimulated. It works by stopping the enzyme . 50mg (Viagra Connect). The standard dose, the 50mg Viagra is sold over the counter as Viagra Connect. 74% of men who use the 50mg dose can achieve an . Sildenafil (Viagra). Tadalafil (Cialis). Vardenafil. These medicines are called PDE5 inhibitors. They enhance the effects of a chemical the body makes that relaxes .