Psychological factors like stress, depression, or anxiety can also contribute. Vardenafil usually works for 4 to 5 hours. Most erectile dysfunction medications belong to the drug class known as PDE5 inhibitors , which help relax the muscles and increase blood flow to allow for a full erection. For more information, work with a member of our medical team who can order lab tests to look for any critical underlying problems. Its effects might last longer if you have mild to moderate ED. Other conditions that may disqualify you from an ED prescription include a history of stroke, kidney or liver disease, cancer, diabetes, or a bleeding disorder.Brand name: $ to $1, for ten to thirty 10 mg tablets Generic: $ to $ for ten 10 mg tablets But your out-of-pocket cost for Levitra may depend on a few . Oral medicines for ED usually work well and cause few side effects. The four main medicines taken by mouth for erectile dysfunction are: Avanafil (Stendra). Sildenafil . For now, we’ll check out the oral options available by prescription only. The oral prescription meds used to treat ED are called PDE-5 inhibitors. ED pills are sold under brand names .